Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CXCR4C-X-C chemokine receptor type 4. (359 aa)    
Predicted Functional Partners:
CXCL12
Stromal cell-derived factor 1.
    
 0.999
ACKR3
C-X-C chemokine receptor type 7 (atypical chemokine receptor 3).
    
 0.953
GNA12
Guanine nucleotide-binding protein subunit alpha-12 isoform X1.
    
 0.920
GNA13
Guanine nucleotide-binding protein subunit alpha-13.
    
 0.920
ITCH
E3 ubiquitin-protein ligase Itchy homolog isoform X1.
    
 
 0.910
LOC110084638
T-cell surface glycoprotein CD4-like isoform X1.
      
 0.906
ARRB2
Arrestin beta 2.
    
 0.865
ARRB1
Arrestin beta 1.
    
 0.865
CD44
CD44 antigen isoform X1.
      
 0.856
CD40LG
Tumor necrosis factor ligand superfamily member 5.
      
 0.755
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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