Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CLOCKCircadian locomoter output cycles protein kaput isoform X1. (885 aa)    
Predicted Functional Partners:
ARNTL
Aryl hydrocarbon receptor nuclear translocator-like protein 1.
   
 0.922
CRY2
Cryptochrome-2.
   
 0.914
ARNTL2
Aryl hydrocarbon receptor nuclear translocator-like protein 2 isoform X1.
   
 0.861
BHLHE41
Class E basic helix-loop-helix protein 41.
    
 0.859
SIRT1
Sirtuin 1.
    
 0.840
CRY1
Cryptochrome-1.
   
 0.796
LOC110085830
Deoxyribodipyrimidine photo-lyase.
   
 0.785
LOC110073388
Cryptochrome-1-like.
   
 0.785
CSNK1D
Casein kinase I isoform X1.
    
 0.733
CSNK1E
Casein kinase 1, epsilon.
    
 0.733
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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