Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EN2Homeobox protein engrailed-2. (297 aa)    
Predicted Functional Partners:
HOXD10
Homeobox protein Hox-D10 isoform X1.
   
 
 0.598
FGF8
Fibroblast growth factor 8 isoform X1.
    
 
 0.574
WNT1
Wingless-type MMTV integration site family, member 1.
    
 
 0.504
FOXA1
Forkhead box A1.
    
 
 0.471
FGF21
Fibroblast growth factor 21.
    
 
 0.437
SLC30A3
Solute carrier family 30 (zinc transporter), member 3.
      
 0.434
LMBR1
Limb region 1 protein homolog.
      
 0.433
LMBR1L
Protein LMBR1L isoform X1.
      
 0.433
CRIM1
Cysteine-rich motor neuron 1 protein.
      
 0.430
MAN2B1
Lysosomal alpha-mannosidase isoform X1.
      
 0.424
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
Server load: low (18%) [HD]