STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
INSIG1Insulin-induced gene 1 protein. (330 aa)    
Predicted Functional Partners:
CHAF1B
Chromatin assembly factor 1 subunit B isoform X1.
    
 0.921
SCAP
Sterol regulatory element-binding protein cleavage-activating protein.
   
 0.858
HMGCR
3-hydroxy-3-methylglutaryl-coenzyme A reductase-like.
   
 
 0.802
RBBP4
Histone-binding protein RBBP4 isoform X1.
    
 0.702
LOC110078097
WD repeat-containing protein 73-like.
    
 0.702
NPC1L1
Niemann-Pick C1-like protein 1.
   
 0.665
NPC1
Niemann-Pick C1 protein.
   
 0.665
SREBF1
Sterol regulatory element-binding transcription factor 1.
   
 0.662
SREBF2
Sterol regulatory element-binding transcription factor 2.
   
 0.662
ORC3
Origin recognition complex subunit 3 isoform X1.
    
   0.569
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.