Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
INSIG1Insulin-induced gene 1 protein. (330 aa)    
Predicted Functional Partners:
SCAP
Sterol regulatory element-binding protein cleavage-activating protein.
    
 0.881
HMGCR
3-hydroxy-3-methylglutaryl-coenzyme A reductase-like.
   
 
 0.878
CHAF1B
Chromatin assembly factor 1 subunit B isoform X1.
   
 
 0.744
PCNA
Proliferating cell nuclear antigen isoform X1.
    
 
 0.694
VCP
Transitional endoplasmic reticulum ATPase isoform X1.
   
 
 0.692
RNF139
E3 ubiquitin-protein ligase RNF139.
    
 
 0.648
FAF2
FAS-associated factor 2 isoform X1.
    
 
 0.638
SYVN1
E3 ubiquitin-protein ligase synoviolin isoform X1.
    
 
 0.624
AMFR
Autocrine motility factor receptor.
    
 
 0.624
CITED2
Cbp/p300-interacting transactivator 2.
      
 0.594
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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