Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC1100701571-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1-like. (1164 aa)    
Predicted Functional Partners:
EGFR
Epidermal growth factor receptor.
    
 0.960
ITPR2
Inositol 1,4,5-trisphosphate receptor type 2 isoform X1.
     
 0.926
ITPR3
Inositol 1,4,5-trisphosphate receptor type 3 isoform X1.
     
 0.926
ITPR1
Inositol 1,4,5-trisphosphate receptor type 1 isoform X1.
     
 0.926
INPP5A
Type I inositol 1,4,5-trisphosphate 5-phosphatase isoform X1.
     
 0.920
ENSPVIP00000011055
Immunoglobulin alpha-2 heavy chain-like.
    
  0.914
PRKCA
Protein kinase C alpha type isoform X1.
   
 0.912
PRKCB
Protein kinase C beta.
   
 0.912
PRKCG
Classical protein kinase C gamma type.
   
 0.912
PTEN
Phosphatase and tensin homolog.
     
 0.909
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
Server load: low (32%) [HD]