Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NRG1Pro-neuregulin-1, membrane-bound isoform isoform X1. (692 aa)    
Predicted Functional Partners:
ERBB4
Receptor tyrosine-protein kinase erbB-4.
    
 0.976
ERBB3
Receptor tyrosine-protein kinase erbB-3.
    
 0.976
ENSPVIP00000008724
annotation not available
    
 0.773
ERBB2
Receptor tyrosine-protein kinase erbB-2 isoform X1.
    
 0.773
EGFR
Epidermal growth factor receptor.
    
 0.773
EGF
LOW QUALITY PROTEIN: pro-epidermal growth factor.
    
 0.677
EREG
Proepiregulin isoform X1.
    
 0.658
NRG4
Pro-neuregulin-4, membrane-bound isoform isoform X1.
    
 0.587
RNF41
E3 ubiquitin-protein ligase NRDP1.
    
 0.586
BTC
Probetacellulin isoform X1.
     
 0.580
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.