Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MSH6DNA mismatch repair protein Msh6 isoform X1. (1322 aa)    
Predicted Functional Partners:
MSH2
DNA mismatch repair protein MSH2.
  
0.997
MLH1
DNA mismatch repair protein MLH1.
 
 0.993
PMS2
Mismatch repair endonuclease PMS2.
  
 0.978
PCNA
Proliferating cell nuclear antigen isoform X1.
   
 0.978
PMS1
PMS1 protein homolog 1 isoform X1.
 
 0.976
EXO1
Exonuclease 1 isoform X1.
   
 0.916
ENSPVIP00000020409
annotation not available
   
 
 0.888
FANCM
Fanconi anemia group M protein.
   
 
 0.888
RPA1
Replication protein A 70 kDa DNA-binding subunit.
   
 0.883
POLD1
DNA polymerase delta catalytic subunit.
   
 
 0.867
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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