Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
RNF170E3 ubiquitin-protein ligase RNF170 isoform X1. (256 aa)    
Predicted Functional Partners:
TMUB1
Transmembrane and ubiquitin-like domain-containing protein 1.
    
 
 0.948
ERLIN1
Erlin-1-like.
    
 
 0.854
ERLIN2
Erlin-2.
    
 
 0.854
C6orf120
UPF0669 protein C6orf120 homolog.
      
 0.697
TMUB2
Transmembrane and ubiquitin-like domain-containing protein 2.
    
 
 0.683
HERPUD2
HERPUD family member 2.
      
 0.655
PPP1R26
Protein phosphatase 1 regulatory subunit 26.
      
 0.629
CABP4
Calcium-binding protein 1/2/4/5.
      
 0.623
PPM1E
Protein phosphatase 1E.
      
 0.621
CGRRF1
Cell growth regulator with RING finger domain protein 1.
      
 0.620
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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