RHEB protein (Pogona vitticeps) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

RHEB

Ras homolog enriched in brain. (185 aa)

Predicted Functional Partners:

TSC2

0.986

MTOR

0.982

RPTOR

0.977

MLST8

0.971

AKT1S1

0.958

BNIP3

0.930

TBC1D7

0.929

LOC110087581

0.917

DEPTOR

0.917

TSC1

0.861

Your Current Organism:

Pogona vitticeps

NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1S1	DEPTOR	ENSPVIP00000020271	ENSPVIP00000024506	Proline-rich AKT1 substrate 1.	DEP domain-containing mTOR-interacting protein.	0.880
AKT1S1	LOC110087581	ENSPVIP00000020271	ENSPVIP00000019259	Proline-rich AKT1 substrate 1.	DEP domain-containing mTOR-interacting protein-like.	0.880
AKT1S1	MLST8	ENSPVIP00000020271	ENSPVIP00000007362	Proline-rich AKT1 substrate 1.	Target of rapamycin complex subunit LST8 isoform X1.	0.998
AKT1S1	MTOR	ENSPVIP00000020271	ENSPVIP00000028203	Proline-rich AKT1 substrate 1.	Serine/threonine-protein kinase mTOR isoform X1.	0.999
AKT1S1	RHEB	ENSPVIP00000020271	ENSPVIP00000004233	Proline-rich AKT1 substrate 1.	Ras homolog enriched in brain.	0.958
AKT1S1	RPTOR	ENSPVIP00000020271	ENSPVIP00000010783	Proline-rich AKT1 substrate 1.	Regulatory-associated protein of mTOR isoform X1.	0.999
AKT1S1	TSC1	ENSPVIP00000020271	ENSPVIP00000018365	Proline-rich AKT1 substrate 1.	TSC complex subunit 1.	0.562
AKT1S1	TSC2	ENSPVIP00000020271	ENSPVIP00000007350	Proline-rich AKT1 substrate 1.	Tuberous sclerosis 2.	0.612
BNIP3	RHEB	ENSPVIP00000016320	ENSPVIP00000004233	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3.	Ras homolog enriched in brain.	0.930
DEPTOR	AKT1S1	ENSPVIP00000024506	ENSPVIP00000020271	DEP domain-containing mTOR-interacting protein.	Proline-rich AKT1 substrate 1.	0.880
DEPTOR	LOC110087581	ENSPVIP00000024506	ENSPVIP00000019259	DEP domain-containing mTOR-interacting protein.	DEP domain-containing mTOR-interacting protein-like.	0.901
DEPTOR	MLST8	ENSPVIP00000024506	ENSPVIP00000007362	DEP domain-containing mTOR-interacting protein.	Target of rapamycin complex subunit LST8 isoform X1.	0.941
DEPTOR	MTOR	ENSPVIP00000024506	ENSPVIP00000028203	DEP domain-containing mTOR-interacting protein.	Serine/threonine-protein kinase mTOR isoform X1.	0.981
DEPTOR	RHEB	ENSPVIP00000024506	ENSPVIP00000004233	DEP domain-containing mTOR-interacting protein.	Ras homolog enriched in brain.	0.917
DEPTOR	RPTOR	ENSPVIP00000024506	ENSPVIP00000010783	DEP domain-containing mTOR-interacting protein.	Regulatory-associated protein of mTOR isoform X1.	0.942
LOC110087581	AKT1S1	ENSPVIP00000019259	ENSPVIP00000020271	DEP domain-containing mTOR-interacting protein-like.	Proline-rich AKT1 substrate 1.	0.880
LOC110087581	DEPTOR	ENSPVIP00000019259	ENSPVIP00000024506	DEP domain-containing mTOR-interacting protein-like.	DEP domain-containing mTOR-interacting protein.	0.901
LOC110087581	MLST8	ENSPVIP00000019259	ENSPVIP00000007362	DEP domain-containing mTOR-interacting protein-like.	Target of rapamycin complex subunit LST8 isoform X1.	0.941
LOC110087581	MTOR	ENSPVIP00000019259	ENSPVIP00000028203	DEP domain-containing mTOR-interacting protein-like.	Serine/threonine-protein kinase mTOR isoform X1.	0.981
LOC110087581	RHEB	ENSPVIP00000019259	ENSPVIP00000004233	DEP domain-containing mTOR-interacting protein-like.	Ras homolog enriched in brain.	0.917