Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ZFYVE9MAD, mothers against decapentaplegic interacting protein. (1420 aa)    
Predicted Functional Partners:
SMAD2
SMAD family member 2.
   
 0.979
ZFYVE16
MAD, mothers against decapentaplegic interacting protein.
     
 
0.900
SMAD3
SMAD family member 3.
   
 0.801
TGFBR1
TGF-beta receptor type-1 isoform X1.
   
 0.778
SMAD9
Mothers against decapentaplegic homolog 9.
   
 0.694
SMAD1
Mothers against decapentaplegic homolog 1.
   
 0.694
ENSPVIP00000031951
annotation not available
    
 0.686
SMAD4
Mothers against decapentaplegic homolog 4 isoform X1.
    
 0.686
BMPR2
Bone morphogenetic protein receptor type-2.
    
 0.636
TGFBR2
TGF-beta receptor type-2.
    
 0.628
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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