Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PREX2Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein. (1457 aa)    
Predicted Functional Partners:
CDC42
Cell division control protein 42 homolog isoform X1.
    
 0.809
RAC1
Ras-related C3 botulinum toxin substrate 1.
    
 0.757
RAC3
Ras-related C3 botulinum toxin substrate 3.
    
 0.757
RAC2
Ras-related C3 botulinum toxin substrate 2.
    
 0.757
VAPB
Vesicle-associated membrane protein-associated protein B/C.
    
   0.737
VAPA
Vesicle-associated membrane protein-associated protein A.
    
   0.737
LOC110080213
Rho-related GTP-binding protein RhoG-like.
    
 0.678
ENSPVIP00000028814
annotation not available
    
 0.678
LOC110078152
Rho-related GTP-binding protein RhoG-like.
    
 0.678
ITSN1
Intersectin-1 isoform X1.
    
 0.662
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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