Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CDKN2CCyclin-dependent kinase 4 inhibitor C. (159 aa)    
Predicted Functional Partners:
CCND1
G1/S-specific cyclin-D1.
    
 0.994
CDK4
Cyclin-dependent kinase 4.
   
 0.991
CDK6
Cyclin-dependent kinase 6.
   
 0.991
CCND3
G1/S-specific cyclin-D3.
    
 0.986
LOC110078878
G1/S-specific cyclin-D3-like isoform X1.
    
 0.986
CDK3
Cyclin-dependent kinase 3 isoform X1.
   
 0.726
CDK2
Cyclin-dependent kinase 2 isoform X1.
   
 0.726
CDK1
Cyclin-dependent kinase 1.
   
 0.709
CDA
Cytidine deaminase.
    
  0.622
MCM6
DNA replication licensing factor MCM6.
    
 
 0.620
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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