Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ANKRD12Ankyrin repeat domain-containing protein 12 isoform X1. (2025 aa)    
Predicted Functional Partners:
BRCA1
Breast cancer type 1 susceptibility protein.
   
 0.796
RBBP8
DNA endonuclease RBBP8.
    
 0.720
TOPBP1
DNA topoisomerase 2-binding protein 1 isoform X1.
   
 0.707
BRCA2
Breast cancer type 2 susceptibility protein.
   
 0.702
RAD51
DNA repair protein RAD51 homolog 1.
   
 0.691
ABRAXAS1
BRCA1-A complex subunit Abraxas isoform X1.
    
 0.652
TP53
Cellular tumor antigen p53.
    
 0.648
MRE11
Double-strand break repair protein MRE11.
   
 0.646
BRCC3
BRCA1/BRCA2-containing complex subunit 3.
    
 0.631
NBN
Nibrin isoform X1.
    
 0.624
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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