Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IBSPIntegrin binding sialoprotein. (331 aa)    
Predicted Functional Partners:
ITGB3
Integrin subunit beta 3.
    
 0.957
ITGB5
Integrin beta 5.
    
 0.947
ITGAV
Integrin alpha V.
     
 0.944
SPP1
Secreted phosphoprotein 1.
  
   
 0.894
ENSPVIP00000009410
annotation not available
   
  
 0.858
ENSPVIP00000004588
annotation not available
   
  
 0.820
PKD2
Polycystin 2.
   
 
 0.795
ITGB1
Integrin beta-1 isoform X1.
    
 0.764
ITGB7
Integrin beta-7 isoform X1.
    
 0.764
ITGB4
Integrin subunit beta 4.
    
  0.739
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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