Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ERCC6DNA excision repair protein ERCC-6 isoform X1. (1474 aa)    
Predicted Functional Partners:
ERCC8
DNA excision repair protein ERCC-8 isoform X1.
    
 0.997
XPA
DNA repair protein complementing XP-A cells isoform X1.
    
 0.972
POLR2I
DNA-directed RNA polymerase II subunit RPB9.
    
 0.972
POLR2A
DNA-directed RNA polymerase II subunit RPB1.
    
 0.970
RPS27A
Ribosomal protein S27a.
    
  0.952
POLR2D
DNA-directed RNA polymerase II subunit RPB4.
    
 0.946
POLR2B
DNA-directed RNA polymerase II subunit RPB2.
    
 0.941
LOC110080008
DNA repair protein complementing XP-G cells-like.
   
 0.934
BIVM
Basic immunoglobulin-like variable motif-containing protein.
   
 0.934
DDB1
DNA damage-binding protein 1 isoform X1.
    
 0.933
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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