Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MLKLMixed lineage kinase domain-like protein. (445 aa)    
Predicted Functional Partners:
RIPK3
Receptor-interacting serine/threonine-protein kinase 3 isoform X1.
  
 
0.953
HSP90AB1
Heat shock protein HSP 90-beta.
    
 0.925
HSP90AA1
Heat shock protein HSP 90-alpha.
    
 0.925
VPS4A
Vacuolar protein sorting-associated protein 4A.
    
  0.903
VPS4B
Vacuolar protein sorting-associated protein 4B.
    
  0.903
CHMP2A
Charged multivesicular body protein 2A.
    
 0.902
CHMP4A
Charged multivesicular body protein 4a.
    
 0.902
CHMP6
Charged multivesicular body protein 6 isoform X1.
     
 0.901
TRPM7
Transient receptor potential cation channel subfamily M member 7.
     
 0.901
LOC110086647
Charged multivesicular body protein 1b-2-like.
     
  0.900
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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