Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SOS2Son of sevenless homolog 2. (1319 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor-binding protein 2.
    
 0.999
EGFR
Epidermal growth factor receptor.
    
 0.983
NRAS
GTPase NRas isoform X1.
   
 0.959
FGFR3
Fibroblast growth factor receptor 3 isoform X1.
    
 0.959
LOC110078528
GTPase HRas-like.
   
 0.959
HRAS
GTPase HRas.
   
 0.959
FGFR2
Fibroblast growth factor receptor 2 isoform X1.
    
 0.948
FGFR1
Fibroblast growth factor receptor 1 isoform X1.
    
 0.948
MRAS
Ras-related protein M-Ras.
    
 0.946
FGFR4
Fibroblast growth factor receptor 4.
    
 0.946
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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