Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NEFMNeurofilament medium polypeptide (neurofilament 3). (996 aa)    
Predicted Functional Partners:
NEFL
Neurofilament light polypeptide isoform X1.
   
 
 0.814
NES
Nestin.
    
 0.629
GAN
Kelch-like protein 16 (gigaxonin).
    
 
 0.608
GRIN1
Glutamate receptor ionotropic, NMDA 1.
   
  0.584
GFAP
Glial fibrillary acidic protein.
   
   0.580
ENSPVIP00000014897
annotation not available
   
 
 0.489
CDK5
Cyclin-dependent-like kinase 5.
    
 
 0.474
PPP2R2C
Protein phosphatase 2, regulatory subunit B, gamma isoform X1.
   
 0.463
HTR2A
5-hydroxytryptamine receptor 2A.
   
 0.436
SFRP2
Secreted frizzled-related protein 2.
    
 
 0.434
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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