STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DET1DET1 homolog isoform X1. (565 aa)    
Predicted Functional Partners:
COP1
E3 ubiquitin-protein ligase RFWD2.
    
 0.992
DDB1
DNA damage-binding protein 1 isoform X1.
    
 
 0.955
DDB2
DNA damage-binding protein 2 isoform X1.
     
 0.953
ERCC8
DNA excision repair protein ERCC-8 isoform X1.
     
 0.905
RBX1
E3 ubiquitin-protein ligase RBX1.
    
 
 0.900
ETV5
ETS translocation variant 5 isoform X1.
    
 
 0.871
DDA1
DET1- and DDB1-associated protein 1.
    
 
 0.864
STK40
Serine/threonine-protein kinase 40.
    
 
 0.863
CUL4A
Cullin-4A.
    
 
 0.791
CUL4B
Cullin-4B.
    
 
 0.791
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.