NTRK3 protein (Pogona vitticeps) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

NTRK3

Neurotrophic tyrosine kinase, receptor type 3. (757 aa)

Predicted Functional Partners:

NTF4

0.896

BDNF

0.893

NTF3

0.869

PTPRD

0.765

PTPRD-2

0.765

PTPRF

0.765

ENSPVIP00000031626

0.765

PTPRS

0.765

SQSTM1

0.708

GRB2

0.698

Your Current Organism:

Pogona vitticeps

NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BDNF	GRB2	ENSPVIP00000034922	ENSPVIP00000001151	Brain-derived neurotrophic factor isoform X1.	Growth factor receptor-binding protein 2.	0.637
BDNF	NTF3	ENSPVIP00000034922	ENSPVIP00000025461	Brain-derived neurotrophic factor isoform X1.	Neurotrophin-3 isoform X1.	0.956
BDNF	NTF4	ENSPVIP00000034922	ENSPVIP00000031313	Brain-derived neurotrophic factor isoform X1.	Neurotrophin 4.	0.968
BDNF	NTRK3	ENSPVIP00000034922	ENSPVIP00000005239	Brain-derived neurotrophic factor isoform X1.	Neurotrophic tyrosine kinase, receptor type 3.	0.893
ENSPVIP00000031626	GRB2	ENSPVIP00000031626	ENSPVIP00000001151	annotation not available	Growth factor receptor-binding protein 2.	0.521
ENSPVIP00000031626	NTRK3	ENSPVIP00000031626	ENSPVIP00000005239	annotation not available	Neurotrophic tyrosine kinase, receptor type 3.	0.765
GRB2	BDNF	ENSPVIP00000001151	ENSPVIP00000034922	Growth factor receptor-binding protein 2.	Brain-derived neurotrophic factor isoform X1.	0.637
GRB2	ENSPVIP00000031626	ENSPVIP00000001151	ENSPVIP00000031626	Growth factor receptor-binding protein 2.	annotation not available	0.521
GRB2	NTF4	ENSPVIP00000001151	ENSPVIP00000031313	Growth factor receptor-binding protein 2.	Neurotrophin 4.	0.450
GRB2	NTRK3	ENSPVIP00000001151	ENSPVIP00000005239	Growth factor receptor-binding protein 2.	Neurotrophic tyrosine kinase, receptor type 3.	0.698
GRB2	PTPRD	ENSPVIP00000001151	ENSPVIP00000005696	Growth factor receptor-binding protein 2.	Protein tyrosine phosphatase receptor type D.	0.521
GRB2	PTPRD-2	ENSPVIP00000001151	ENSPVIP00000005723	Growth factor receptor-binding protein 2.	Receptor-type tyrosine-protein phosphatase delta isoform X1.	0.521
GRB2	PTPRF	ENSPVIP00000001151	ENSPVIP00000030459	Growth factor receptor-binding protein 2.	Receptor-type tyrosine-protein phosphatase F isoform X1.	0.521
GRB2	PTPRS	ENSPVIP00000001151	ENSPVIP00000031770	Growth factor receptor-binding protein 2.	Receptor-type tyrosine-protein phosphatase S isoform X1.	0.521
NTF3	BDNF	ENSPVIP00000025461	ENSPVIP00000034922	Neurotrophin-3 isoform X1.	Brain-derived neurotrophic factor isoform X1.	0.956
NTF3	NTF4	ENSPVIP00000025461	ENSPVIP00000031313	Neurotrophin-3 isoform X1.	Neurotrophin 4.	0.495
NTF3	NTRK3	ENSPVIP00000025461	ENSPVIP00000005239	Neurotrophin-3 isoform X1.	Neurotrophic tyrosine kinase, receptor type 3.	0.869
NTF4	BDNF	ENSPVIP00000031313	ENSPVIP00000034922	Neurotrophin 4.	Brain-derived neurotrophic factor isoform X1.	0.968
NTF4	GRB2	ENSPVIP00000031313	ENSPVIP00000001151	Neurotrophin 4.	Growth factor receptor-binding protein 2.	0.450
NTF4	NTF3	ENSPVIP00000031313	ENSPVIP00000025461	Neurotrophin 4.	Neurotrophin-3 isoform X1.	0.495