Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DEGS2Sphingolipid delta(4)-desaturase/C4-monooxygenase DES2. (323 aa)    
Predicted Functional Partners:
KDSR
3-ketodihydrosphingosine reductase isoform X1.
   
 
 0.941
GALC
Galactocerebrosidase isoform X1.
     
 0.939
SAMD8
Sphingomyelin synthase-related protein 1 isoform X1.
   
 
 0.938
ASAH1
Acid ceramidase.
     
 0.936
SMPD1
Sphingomyelin phosphodiesterase 1.
     
 0.934
UGT8
2-hydroxyacylsphingosine 1-beta-galactosyltransferase.
     
 0.933
UGCG
Ceramide glucosyltransferase isoform X1.
   
 
 0.933
SMPD2
Sphingomyelin phosphodiesterase 2 isoform X1.
     
 0.932
CERS5
Sphingoid base N-palmitoyltransferase.
   
 0.931
CERS6
Ceramide synthase 6.
   
 0.931
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.