Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RFX6DNA-binding protein RFX6 isoform X1. (921 aa)    
Predicted Functional Partners:
MLXIPL
Carbohydrate-responsive element-binding protein.
      
 0.694
PCSK1
Proprotein convertase subtilisin/kexin type 1.
      
 0.665
INS
Insulin.
     
 0.662
NEUROG1
Neurogenin 1.
   
  
 0.588
GLIS3
Zinc finger protein GLIS1/3.
    
 
 0.574
RFXAP
Regulatory factor X associated protein.
    
 
 0.569
RFXANK
Regulatory factor X-associated ankyrin-containing protein.
    
 
 0.569
NKX2-2
Homeobox protein Nkx-2.2.
      
 0.568
PTF1A
Pancreas transcription factor 1 subunit alpha.
      
 0.568
FEV
ETS oncogene family protein FEV.
   
  
 0.526
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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