STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IGF1RInsulin like growth factor 1 receptor. (1255 aa)    
Predicted Functional Partners:
INS
Insulin.
    
 0.864
PTPN1
Protein tyrosine phosphatase non-receptor type 1.
   
 0.808
IGF2
Insulin-like growth factor II isoform X1.
    
 0.806
PTPN2
Tyrosine-protein phosphatase non-receptor type 2 isoform X1.
   
 0.761
IRS4
Insulin receptor substrate 2.
   
 0.736
LOC110082325
Insulin receptor substrate 1-like.
   
 0.736
IRS2
Insulin receptor substrate 2.
   
 0.736
IRS1
Insulin receptor substrate 1.
   
 0.736
SHC3
SHC-transforming protein 3 isoform X1.
    
 0.708
SHC1
LOW QUALITY PROTEIN: SHC-transforming protein 1.
    
 0.708
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.