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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KSR2Kinase suppressor of Ras 2 isoform X1. (918 aa)    
Predicted Functional Partners:
MAP2K2
Dual specificity mitogen-activated protein kinase kinase 2.
   
 0.801
MAP2K1
Mitogen-activated protein kinase kinase 1.
   
 0.801
MAP2K5
Dual specificity mitogen-activated protein kinase kinase 5.
   
0.801
PPP5C
Serine/threonine-protein phosphatase 5.
   
 0.738
YWHAB
14-3-3 protein beta/theta/zeta.
   
 0.728
ARAF
A-Raf proto-oncogene serine/threonine-protein kinase.
    
0.673
RAF1
RAF proto-oncogene serine/threonine-protein kinase isoform X1.
    
0.673
BRAF
B-Raf proto-oncogene serine/threonine-protein kinase.
    
0.673
CNKSR1
Connector enhancer of kinase suppressor of Ras 1.
    
 0.647
YWHAZ
14-3-3 protein beta/theta/zeta.
   
 0.641
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.