Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KSR2Kinase suppressor of Ras 2 isoform X1. (918 aa)    
Predicted Functional Partners:
MAP2K2
Dual specificity mitogen-activated protein kinase kinase 2.
   
 0.826
MAP2K1
Mitogen-activated protein kinase kinase 1.
   
 0.826
MAP2K5
Dual specificity mitogen-activated protein kinase kinase 5.
   
 0.820
BRAP
BRCA1-associated protein.
    
 0.815
CNKSR1
Connector enhancer of kinase suppressor of Ras 1.
    
 0.783
ARAF
A-Raf proto-oncogene serine/threonine-protein kinase.
    
 0.748
RAF1
RAF proto-oncogene serine/threonine-protein kinase isoform X1.
    
 0.748
BRAF
B-Raf proto-oncogene serine/threonine-protein kinase.
    
 0.748
LOC110088228
Connector enhancer of kinase suppressor of ras 2-like.
    
 0.727
CNKSR2
Connector enhancer of kinase suppressor of ras 2 isoform X1.
    
 0.727
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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