STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AREGAmphiregulin. (219 aa)    
Predicted Functional Partners:
EGFR
Epidermal growth factor receptor.
    
 0.969
EREG
Proepiregulin isoform X1.
  
 
 0.967
BTC
Probetacellulin isoform X1.
     
 0.930
ERBB4
Receptor tyrosine-protein kinase erbB-4.
    
 0.895
ERBB2
Receptor tyrosine-protein kinase erbB-2 isoform X1.
    
 0.895
ERBB3
Receptor tyrosine-protein kinase erbB-3.
    
 0.895
EGF
LOW QUALITY PROTEIN: pro-epidermal growth factor.
     
 0.830
TGFA
Transforming growth factor alpha.
     
 0.814
SEC24D
Protein transport protein Sec24D.
     
  0.739
SEC24A
Protein transport protein Sec24A isoform X1.
     
  0.739
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.