Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ARRDC4Arrestin domain-containing protein 4. (327 aa)    
Predicted Functional Partners:
WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2 isoform X1.
    
 
 0.772
ITCH
E3 ubiquitin-protein ligase Itchy homolog isoform X1.
    
 
 0.762
WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1 isoform X1.
    
 
 0.756
LOC110077729
Thioredoxin-like.
    
 0.689
AQP4
Aquaporin-4 isoform X1.
      
 0.621
CUEDC1
CUE domain-containing protein 1.
    
   0.612
AQP8
Aquaporin-8 isoform X1.
      
 0.610
ENSPVIP00000006897
NACHT, LRR and PYD domains-containing protein 9B-like.
    
 0.601
TSG101
Tumor susceptibility gene 101 protein isoform X1.
   
 
 0.538
D2HGDH
D-2-hydroxyglutarate dehydrogenase, mitochondrial.
    
 
 0.531
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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