STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TBK1LOW QUALITY PROTEIN: serine/threonine-protein kinase TBK1. (719 aa)    
Predicted Functional Partners:
IRF3
Interferon regulatory factor 3.
    
 0.996
STING1
Stimulator of interferon genes protein.
   
 0.995
TRAF3
TNF receptor-associated factor 3 isoform X1.
   
 0.994
OPTN
Optineurin.
   
 0.990
TANK
TRAF family member-associated NF-kappa-B activator isoform X1.
   
 0.988
SQSTM1
Sequestosome-1 isoform X1.
    
 0.986
IRF7
Interferon regulatory factor 7.
   
 0.978
CALCOCO2
Calcium-binding and coiled-coil domain-containing protein 2.
    
 0.949
RELA
Transcription factor p65.
   
 0.940
NFKB1
Nuclear factor NF-kappa-B p105 subunit isoform X1.
   
 0.936
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.