Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TRIB2Tribbles homolog 1/2. (333 aa)    
Predicted Functional Partners:
COP1
E3 ubiquitin-protein ligase RFWD2.
    
 
 0.815
FOSL2
Fos-related antigen 2 isoform X1.
   
 0.738
STK40
Serine/threonine-protein kinase 40.
    
 
 0.737
ATF4
Cyclic AMP-dependent transcription factor ATF-4.
   
 0.711
AKT1
RAC-alpha serine/threonine-protein kinase.
    
 0.650
AKT2
RAC-beta serine/threonine-protein kinase.
    
 0.650
AKT3
RAC-gamma serine/threonine-protein kinase isoform X1.
    
 0.650
ENSPVIP00000032337
annotation not available
    
 0.650
DET1
DET1 homolog isoform X1.
    
 
 0.629
CHAC1
Glutathione-specific gamma-glutamylcyclotransferase 1.
   
 
 0.618
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.