Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GREB1Protein GREB1 isoform X1. (1933 aa)    
Predicted Functional Partners:
CREBBP
CREB-binding protein isoform X1.
    
 0.938
ESR1
Estrogen receptor isoform X1.
    
 0.934
EP300
Histone acetyltransferase p300 isoform X1.
    
 0.907
ESR2
Estrogen receptor beta.
    
 0.651
CYP19A1
Aromatase.
      
 0.636
PGR
Progesterone receptor.
   
 0.633
ANKRD55
Ankyrin repeat domain-containing protein 55.
      
 0.608
STN1
CST complex subunit STN1.
      
 0.600
SH3RF3
SH3 domain-containing RING finger protein 3 isoform X1.
      
 0.599
WNT4
Wingless-type MMTV integration site family, member 4.
      
 0.583
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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