Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ROCK2Rho-associated protein kinase 2. (1376 aa)    
Predicted Functional Partners:
ROCK1
Rho-associated protein kinase 1 isoform X1.
  
0.999
LOC110081153
Ras homolog gene family, member A.
    
 0.979
RHOA
Ras homolog gene family, member A.
    
 0.979
PPP1R12A
Protein phosphatase 1 regulatory subunit 12A.
   
 0.959
PPP1R12B
Protein phosphatase 1 regulatory subunit 12B isoform X1.
   
 0.959
PPP1R12C
Protein phosphatase 1 regulatory subunit 12C isoform X1.
   
 0.959
LIMK1
LIM domain kinase 1 isoform X1.
    
0.949
LIMK2
LIM domain kinase 2.
    
0.949
MYL10
Myosin regulatory light chain 10.
    
 0.942
MYL2
Myosin regulatory light chain 2, ventricular/cardiac muscle isoform.
    
 0.942
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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