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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDRF1Erythroid differentiation-related factor 1 isoform X1. (1247 aa)    
Predicted Functional Partners:
IGSF5
Immunoglobulin superfamily member 5 isoform X1.
      
 0.523
CSDC2
Cold shock domain-containing protein C2 isoform X1.
      
 0.483
PLPP6
Presqualene diphosphate phosphatase.
      
 0.470
LARP1B
La-related protein 1B isoform X1.
      
 0.445
KCNK5
Potassium channel subfamily K member 5.
      
 0.426
HIKESHI
Protein Hikeshi.
      
 0.420
ENSPVIP00000026957
annotation not available
      
 0.420
GPR182
G-protein coupled receptor 182.
      
 0.416
PACC1
Transmembrane protein 206.
      
 0.402
ING4
Inhibitor of growth protein 4 isoform X1.
      
 0.402
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.