Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PDPRPyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial. (879 aa)    
Predicted Functional Partners:
GCSH
Glycine cleavage system H protein, mitochondrial.
  
 0.907
PDP2
Pyruvate dehydrogenase [acetyl-transferring]-phosphatase 2, mitochondrial.
  
 0.901
PDP1
Pyruvate dehyrogenase phosphatase catalytic subunit 1 isoform X1.
  
 0.901
GLDC
Glycine dehydrogenase (decarboxylating), mitochondrial.
  
 0.892
PDHX
Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex.
  
 
 0.854
DLAT
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase).
  
 
 0.824
NUDCD1
NudC domain-containing protein 1 isoform X1.
    
   0.797
DHFR
Dihydrofolate reductase isoform X1.
  
 
 0.716
SHMT1
Serine hydroxymethyltransferase, cytosolic isoform X1.
  
 0.702
SHMT2
Serine hydroxymethyltransferase, mitochondrial.
  
 0.702
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
Server load: low (10%) [HD]