STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BCKDK3-methyl-2-oxobutanoate dehydrogenase [lipoamide] kinase, mitochondrial. (414 aa)    
Predicted Functional Partners:
BCKDHA
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial.
   
 0.767
BCKDHB
2-oxoisovalerate dehydrogenase subunit beta, mitochondrial.
    
 0.751
DLAT
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase).
    
 0.699
PDHX
Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex.
    
 0.699
PDHA1
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial isoform X1.
    
 0.694
DBT
Dihydrolipoamide branched chain transacylase E2.
    
 0.673
DLD
Dihydrolipoyl dehydrogenase, mitochondrial.
   
 0.658
PDHB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial.
    
 0.650
MAP3K4
Mitogen-activated protein kinase kinase kinase 4 isoform X1.
   
 0.648
DLST
2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase).
    
 0.635
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.