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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PHACTR1Phosphatase and actin regulator 1 isoform X1. (423 aa)    
Predicted Functional Partners:
WDR37
WD repeat domain 37.
      
 0.603
ARMC8
Armadillo repeat-containing protein 8 isoform X1.
      
 0.593
DIP2C
Disco-interacting protein 2 homolog C.
     
 0.569
LRRC45
Leucine-rich repeat-containing protein 45.
      
 0.563
PLCH1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1-like.
      
 0.561
CPLX4
Complexin-3/4.
      
 0.560
HIVEP1
Human immunodeficiency virus type I enhancer-binding protein.
      
 0.557
DMXL2
DmX-like protein 2.
      
 0.475
MRTFB
Myocardin related transcription factor B.
   
  
 0.470
MRTFA
MKL/myocardin-like protein 1 isoform X1.
   
  
 0.470
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.