Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RUNX2RUNX family transcription factor 2. (552 aa)    
Predicted Functional Partners:
CBFB
Core-binding factor subunit beta.
    
 0.939
EP300
Histone acetyltransferase p300 isoform X1.
    
 0.842
TAL1
T-cell acute lymphocytic leukemia protein 1 isoform X1.
    
 0.826
CREBBP
CREB-binding protein isoform X1.
    
 0.791
WWTR1
WW domain-containing transcription regulator protein 1.
    
 0.783
PML
Promyelocytic leukemia.
    
 0.764
STUB1
STIP1 homology and U-box containing protein 1.
    
 0.764
GATA1
GATA binding protein 1.
    
 0.760
SOX9
Transcription factor SOX9 (SOX group E).
   
 0.752
HDAC3
Histone deacetylase 3 isoform X1.
    
 0.746
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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