Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SMC6Structural maintenance of chromosomes protein 6 isoform X1. (1098 aa)    
Predicted Functional Partners:
NSMCE2
E3 SUMO-protein ligase NSE2.
    
 0.998
NSMCE4A
Non-structural maintenance of chromosomes element 4 homolog A.
   
 0.998
SMC5
Structural maintenance of chromosomes protein 5 isoform X1.
   
0.997
NSMCE1
Non-structural maintenance of chromosomes element 1 homolog.
    
 0.996
LOC110078621
Non-structural maintenance of chromosomes element 3 homolog.
   
 0.995
SMC3
Structural maintenance of chromosome 3 (chondroitin sulfate proteoglycan 6).
   
 0.931
RAD51
DNA repair protein RAD51 homolog 1.
   
 
 0.907
MUS81
MUS81 structure-specific endonuclease subunit.
    
 
 0.903
TUFT1
Tuftelin.
    
 
 0.865
TOP3A
DNA topoisomerase 3-alpha.
  
 
 0.863
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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