STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HERC2E3 ubiquitin-protein ligase HERC2 isoform X1. (4835 aa)    
Predicted Functional Partners:
RNF8
E3 ubiquitin-protein ligase RNF8 isoform X1.
   
 0.753
AKAP17A
Splicing factor, arginine/serine-rich 17.
    
 
 0.689
RAP2A
Ras-related protein Rap-2A.
    
 0.689
NIPA2
Magnesium transporter NIPA2 isoform X1.
      
 0.679
UNC50
Protein unc-50 homolog.
      
 0.679
ARHGAP6
Rho GTPase-activating protein 6 isoform X1.
      
 0.679
UXS1
UDP-glucuronic acid decarboxylase 1 isoform X1.
      
 0.679
PIAS4
Protein inhibitor of activated STAT 4.
    
 0.636
UBC
Polyubiquitin-C.
    
 0.602
NEURL4
Neuralized E3 ubiquitin protein ligase 4.
    
 
 0.598
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.