STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HERC2E3 ubiquitin-protein ligase HERC2 isoform X1. (4835 aa)    
Predicted Functional Partners:
RNF8
E3 ubiquitin-protein ligase RNF8 isoform X1.
   
 0.891
NEURL4
Neuralized E3 ubiquitin protein ligase 4.
    
 
 0.820
UBE3A
Ubiquitin-protein ligase E3A isoform X1.
   
 0.802
BRCA1
Breast cancer type 1 susceptibility protein.
    
 0.800
TP53
Cellular tumor antigen p53.
   
 
 0.786
PIAS4
Protein inhibitor of activated STAT 4.
    
 0.739
MAPK6
Mitogen-activated protein kinase 4/6.
    
 0.736
CEP170
Centrosomal protein of 170 kDa isoform X1.
    
 
 0.701
RPA1
Replication protein A 70 kDa DNA-binding subunit.
    
   0.671
RANBP2
RanBP2-like and GRIP domain-containing protein 4 isoform X1.
   
 0.664
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.