Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HTTHuntingtin. (1685 aa)    
Predicted Functional Partners:
LOC110091731
Huntingtin-like.
 
     0.949
CREBBP
CREB-binding protein isoform X1.
   
 0.897
SQSTM1
Sequestosome-1 isoform X1.
    
 
 0.897
VCP
Transitional endoplasmic reticulum ATPase isoform X1.
   
 0.894
OPTN
Optineurin.
    
 
 0.884
SETD2
[histone H3]-dimethyl-L-lysine36 N-methyltransferase.
    
 
 0.839
DSN1
Kinetochore-associated protein DSN1 homolog.
   
 0.833
PRPF40A
Pre-mRNA-processing factor 40 homolog A.
   
 0.816
UBE2K
Ubiquitin-conjugating enzyme (huntingtin interacting protein 2).
    
 0.811
HYPK
Huntingtin-interacting protein K.
    
 
 0.797
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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