Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NPTX2Neuronal pentraxin-2. (433 aa)    
Predicted Functional Partners:
RING1
E3 ubiquitin-protein ligase RNF1/2.
    
 0.616
RNF2
E3 ubiquitin-protein ligase RNF1/2.
    
 0.616
EED
Polycomb protein EED.
    
 0.533
PCGF3
Polycomb group RING finger protein 3.
    
 0.445
PCGF1
Polycomb group RING finger protein 1.
    
 0.445
PCGF2
Polycomb group RING finger protein 2.
    
 0.445
PCGF6
Polycomb group RING finger protein 6.
    
 0.445
PCGF5
Polycomb group RING finger protein 5 isoform X1.
    
 0.445
LOC110083403
Polycomb group RING finger protein 4.
    
 0.445
YAF2
YY1-associated factor 2.
    
 0.426
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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