Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
PAK3Serine/threonine-protein kinase PAK 3. (542 aa)    
Predicted Functional Partners:
CDC42
Cell division control protein 42 homolog isoform X1.
   
 0.996
ARHGEF6
Rho guanine nucleotide exchange factor 6.
   
 0.987
NCK2
Cytoplasmic protein NCK2.
    
 0.987
ARHGEF7
Rho guanine nucleotide exchange factor 7 isoform X1.
   
 0.987
RAC1
Ras-related C3 botulinum toxin substrate 1.
   
 0.973
RAC3
Ras-related C3 botulinum toxin substrate 3.
   
 0.973
RAC2
Ras-related C3 botulinum toxin substrate 2.
   
 0.973
LIMK1
LIM domain kinase 1 isoform X1.
    
0.962
LIMK2
LIM domain kinase 2.
    
0.962
RAF1
RAF proto-oncogene serine/threonine-protein kinase isoform X1.
    
0.957
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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