Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACTBActin, cytoplasmic 1. (375 aa)    
Predicted Functional Partners:
PFN4
Profilin-4.
   
 0.950
CFL2
Cofilin-2.
   
 0.947
CFL1
Cofilin-1.
   
 0.945
VCL
Vinculin isoform X1.
   
 0.945
PFN2
Profilin-2 isoform X1.
   
 0.940
PFN3
Profilin-3.
   
 0.940
WASL
WASP like actin nucleation promoting factor.
    
 0.937
LOC110080639
Neural Wiskott-Aldrich syndrome protein-like isoform X1.
    
 0.937
IQGAP1
Ras GTPase-activating-like protein IQGAP1.
    
 0.937
ACTN1
Alpha-actinin-1 isoform X1.
   
 0.934
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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