Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
UBE3AUbiquitin-protein ligase E3A isoform X1. (877 aa)    
Predicted Functional Partners:
UBE2L3
Ubiquitin-conjugating enzyme E2 L3.
    
 0.976
TP53
Cellular tumor antigen p53.
    
 
 0.971
PSMD4
26S proteasome non-ATPase regulatory subunit 4 isoform X1.
    
 
 0.945
PSMC1
26S proteasome regulatory subunit T2.
    
 
 0.939
ESR1
Estrogen receptor isoform X1.
    
 
 0.934
PSMD14
26S proteasome non-ATPase regulatory subunit 14.
    
 
 0.934
TAT
Tyrosine aminotransferase.
    
   0.927
NEURL4
Neuralized E3 ubiquitin protein ligase 4.
    
 
 0.918
UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5 isoform X1.
    
 
 0.908
PSMD2
26S proteasome non-ATPase regulatory subunit 2.
   
 
 0.908
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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