Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AIFM1Apoptosis-inducing factor 1, mitochondrial isoform X1. (585 aa)    
Predicted Functional Partners:
CHCHD4
Mitochondrial intermembrane space import and assembly protein 40.
    
 
 0.948
BAX
Apoptosis regulator BAX-like isoform X1.
    
 0.916
LOC110078547
Apoptosis regulator BAX-like.
     
  0.900
NDUFS5
NADH dehydrogenase [ubiquinone] iron-sulfur protein 5.
    
 
 0.895
PPIA
Peptidyl-prolyl cis-trans isomerase A (cyclophilin A).
    
 0.891
LOC110077729
Thioredoxin-like.
   
 
 0.877
GSR
Glutathione reductase, mitochondrial.
  
 0.856
OTUD1
OTU deubiquitinase 1.
    
   0.849
LOC110089098
Cytochrome c oxidase subunit 6B1.
    
 
 0.848
EXOG
Nuclease EXOG, mitochondrial isoform X1.
    
 
 0.821
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.