Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ARHGEF12Rho guanine nucleotide exchange factor 12. (1496 aa)    
Predicted Functional Partners:
GNA13
Guanine nucleotide-binding protein subunit alpha-13.
    
 0.988
GNA12
Guanine nucleotide-binding protein subunit alpha-12 isoform X1.
    
 0.981
LOC110081153
Ras homolog gene family, member A.
   
 0.970
RHOA
Ras homolog gene family, member A.
   
 0.970
ARHGEF6
Rho guanine nucleotide exchange factor 6.
   
 0.944
ARHGEF7
Rho guanine nucleotide exchange factor 7 isoform X1.
   
 0.944
MRAS
Ras-related protein M-Ras.
    
 0.914
NRAS
GTPase NRas isoform X1.
    
  0.911
RRAS2
Ras-related protein R-Ras2.
    
  0.911
LOC110078528
GTPase HRas-like.
    
  0.911
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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