Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PMS2Mismatch repair endonuclease PMS2. (855 aa)    
Predicted Functional Partners:
MLH1
DNA mismatch repair protein MLH1.
   
0.999
MSH2
DNA mismatch repair protein MSH2.
 
 0.998
FAN1
Fanconi-associated nuclease 1.
   
 0.993
BRIP1
BRCA1 interacting protein C-terminal helicase 1.
   
 0.984
MSH3
DNA mismatch repair protein MSH3.
 
 0.981
MSH6
DNA mismatch repair protein Msh6 isoform X1.
  
 0.978
EXO1
Exonuclease 1 isoform X1.
   
 0.974
ENSPVIP00000024186
annotation not available
 
 0.965
PCNA
Proliferating cell nuclear antigen isoform X1.
   
 0.961
POLD1
DNA polymerase delta catalytic subunit.
   
 
 0.916
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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