STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BTKBruton agammaglobulinemia tyrosine kinase. (661 aa)    
Predicted Functional Partners:
BLNK
B-cell linker protein isoform X1.
   
 0.898
STAT3
Signal transducer and activator of transcription 3.
   
 0.814
SYK
Tyrosine-protein kinase SYK isoform X1.
   
 0.813
PLCG2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform X1.
   
 0.772
PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1.
   
 0.772
IBTK
Inhibitor of Bruton tyrosine kinase isoform X1.
   
 
 0.739
GRB2
Growth factor receptor-binding protein 2.
    
 0.737
CD3E
T-cell surface glycoprotein CD3 epsilon chain isoform X1.
   
 0.710
ENSPVIP00000019505
annotation not available
   
 0.676
RUFY1
RUN and FYVE domain-containing protein 1 isoform X1.
    
  0.673
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.