Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
MACROD1O-acetyl-ADP-ribose deacetylase MACROD1. (318 aa)    
Predicted Functional Partners:
PARP1
Poly [ADP-ribose] polymerase 1.
    
 
 0.729
GDAP2
Ganglioside-induced differentiation-associated protein 2.
  
   
0.629
TEP1
Telomerase protein component 1 isoform X1.
    
 
 0.610
ADPRHL2
Poly(ADP-ribose) glycohydrolase ARH3 isoform X1.
    
 
 0.583
PARG
Poly(ADP-ribose) glycohydrolase.
      
 0.573
XPC
Xeroderma pigmentosum group C-complementing protein.
    
   0.564
OARD1
O-acetyl-ADP-ribose deacetylase 1 isoform X1.
    
 
 0.557
TMX2
Thioredoxin-related transmembrane protein 2.
   
  
 0.543
ESR1
Estrogen receptor isoform X1.
    
 0.514
AKT1S1
Proline-rich AKT1 substrate 1.
   
    0.512
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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