STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP73Tumor protein p73. (726 aa)    
Predicted Functional Partners:
TP63
Tumor protein 63 isoform X1.
  
 
0.981
MDM2
E3 ubiquitin-protein ligase Mdm2.
    
 0.980
WWTR1
WW domain-containing transcription regulator protein 1.
    
 0.913
IL10RB
Interleukin-10 receptor subunit beta.
    
 0.833
WRN
Werner syndrome ATP-dependent helicase isoform X1.
    
 0.820
BCL2L1
Bcl-2-like 1 (apoptosis regulator Bcl-X).
   
 0.794
RPS27A
Ribosomal protein S27a.
    
  0.791
ITCH
E3 ubiquitin-protein ligase Itchy homolog isoform X1.
    
 0.778
TP53
Cellular tumor antigen p53.
  
 
0.768
CHEK2
Serine/threonine-protein kinase CHEK2.
    
 0.749
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.