Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TSC2Tuberous sclerosis 2. (1765 aa)    
Predicted Functional Partners:
TSC1
TSC complex subunit 1.
   
 0.999
TBC1D7
TBC1 domain family member 7-like.
    
 0.998
PRKAA1
5'-AMP-activated protein kinase catalytic subunit alpha-1.
    
 0.995
DDIT4
DNA damage-inducible transcript 4 protein.
    
 0.993
MTOR
Serine/threonine-protein kinase mTOR isoform X1.
   
 0.988
PRKAA2
5'-AMP-activated protein kinase catalytic subunit alpha-2.
    
 0.987
RHEB
Ras homolog enriched in brain.
    
 0.986
YWHAZ
14-3-3 protein beta/theta/zeta.
    
 0.986
AKT1
RAC-alpha serine/threonine-protein kinase.
    
 0.979
AKT2
RAC-beta serine/threonine-protein kinase.
    
 0.979
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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