Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
E4F1Transcription factor E4F1 / E3 ubiquitin-protein ligase. (720 aa)    
Predicted Functional Partners:
TP53
Cellular tumor antigen p53.
   
 0.873
RPA2
Replication protein A 32 kDa subunit.
    
 0.758
MMS19
MMS19 nucleotide excision repair protein homolog.
      
 0.695
RPL3
Large subunit ribosomal protein L3e.
    
 
 0.692
ASL
Argininosuccinate lyase.
      
 0.671
RPL3L
Large subunit ribosomal protein L3e.
    
 
 0.629
HSF2
Heat shock factor protein 2 isoform X1.
    
 
 0.622
RPL26
Large subunit ribosomal protein L26e.
    
   0.616
MRPS22
28S ribosomal protein S22, mitochondrial isoform X1.
    
  0.597
MRPS23
28S ribosomal protein S23, mitochondrial.
    
  0.590
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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